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Symptoms and signs of tadalafil. Actinomycosis of the tonsils can cause chronic tonsillitis. Thoracic actinomycosis manifests itself as actinomycosis of the lungs with spread to the tissues of cialis. Lung actinomycosis is the second most common form of actinomycosis after oral cavity actinomycosis. It proceeds severely, without treatment leads to death.
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Abdominal actinomycosis in sixty percent of cases is localized in the appendix. In addition to the appendix, the ileocecal region is also primarily affected. Such patients often end up in the surgical department with a diagnosis of appendicitis or intestinal obstruction. The large intestine, stomach, esophagus are affected a second time, the defeat of these sections of the gastrointestinal tract occurs when actinomycetes are introduced from other organs by the hematogenous route and during the germination of granulomas from primary foci.
The abdominal wall is also involved in the process for the second time. Granuloma from the ileocecal region and appendix grows into the liver, kidneys, spine. Fistulous passages often open into the intestinal lumen and the perianal region with the development of paraproctitis. The abdominal form of actinomycosis without treatment in half of the cases leads to death.
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Another form of the disease is actinomycosis of the genitourinary system. It is rare, usually in the form of secondary lesions. Primary foci of actinomycosis in the genitourinary system are almost never found.
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Another rather rare form of actinomycosis is actinomycosis of bones and joints. This form of actinomycosis is the result of granuloma germination from neighboring organs and hematogenous drift. In the affected bone, a picture of osteomyelitis develops with the formation of bone sequesters. Patients with this form of actinomycosis retain the mobility of bones and joints for a long time, even despite their significant damage. During the formation of fistulas, bluish coloration of the skin around the fistula opening attracts attention.
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Actinomycosis of the skin is the next form of actinomycosis. More often it is the result of a generalization of the fungal process. Actinomycosis becomes apparent as soon as the granuloma grows into the subcutaneous fat.
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Madurese foot is a special form of tadalafil process.
Originally found in countries with a tropical climate.
It is characterized by a lesion of the sole of the foot, on which there are nodes the size of a pea.
The skin over the nodes changes its normal color to purplish-purple.
New foci form around the primary nodes, the foot loses its shape due to severe edema.
With the progression of the disease, the formation of fistulous passages occurs, from which purulent or sanious contents flow.
Fistulas open not only from the plantar side, but also on the back surface.
The foot is completely riddled with knots and fistulous passages.
There is a deformity of the fingers upward.
The process is one-sided.
This form of actinomycosis can progress with the involvement of the tendons and muscles of the lower leg in the process.
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A routine blood test for actinomycosis contains information about the sensitization of the body (eosinophilia), as well as the development of severe inflammation (leukocytosis, neutrophilia with a shift to the left, accelerated ESR). In severe forms of actinomycosis, due to a sharp suppression of the immune response, the development of leukopenia, the appearance of toxic granularity in erythrocytes, is possible. A similar picture of the general blood test is typical for patients exhausted by the disease.
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The radiological picture has no pathognomonic signs. The pictures show changes characteristic of pleurisy, abscess. Changes in x-rays in actinomycosis are similar to those in tuberculosis.
The clinical picture, or Tadalafil the appearance of dense subcutaneous metastases, the formation of fistulous tracts with the discharge of purulent contents, helps in making a diagnosis. Actinomycosis of the skin is also accompanied by the formation of microabscesses, the affected tissue acquires a cellular structure. Foci of actinomycosis are punctured. In the resulting punctate, druses, mycelium filaments, characteristic of the radiant fungus, are found.
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Puncture material, as well as discharge from the fistulous passages, sputum is sown on a special nutrient medium to obtain a culture of the fungus. Radiant fungi grow on Sabur, Czapek media, heart-brain agar, on media enriched with blood and serum. Cultivation is carried out in a thermostat at a temperature of 23.5 degrees under anaerobic conditions. The supply of oxygen can stop the growth of colonies. Because Since the material obtained for inoculation often contains associated bacteria, antibiotics are added to the medium to destroy this flora. So Sabouraud's medium contains tetracycline hydrochloride and penicillin.
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The medium for sowing on radiant fungus should be transparent for better viewing. Growth of actinomycetes begins after two to four days, characteristic arachnid colonies are found. During subsequent incubation, typical colonies are formed, this happens by the tenth to fourteenth day. Colony gsmooth, rough, striated, S-curved. When viewed under a microscope, the characteristic filaments of mycelium are determined. Colonies can acquire a variety of shades (crimson, gray, greenish) due to the ability of some actinomycetes to form pigments.
With smear microscopy, it is sometimes possible to see drusen, although their presence is not mandatory. Detection of drusen makes it possible to make a preliminary diagnosis. The preliminary diagnosis is confirmed by obtaining colonies characteristic of the radiant fungus on nutrient media.
Smears from tonsils, gums, carious teeth have no diagnostic value. radiant fungus occurs in similar smears in healthy people. For diagnosis, an intradermal test with actinolysate is valuable. It is positive in eighty percent of patients, may be negative in persons with severe immunodeficiency (severe forms of actinomycosis), in HIV-infected patients, the test with actinolysate is always negative.
If the fistula is open into the lumen of cialis 10 or 20 mg, then in the sputum one can see the characteristic areas of the fungus, resembling grains. Computed tomography is not of great importance for diagnosis; it only helps to suspect the presence of foci of actinomycosis when foci of an inhomogeneous structure are detected. Computed tomography is well suited to monitor changes in lesions during treatment.
Ultrasound of the abdominal organs is also of auxiliary importance for diagnosis; during its implementation, foci of inhomogeneous density are also detected. Treatment of actinomycosis includes the use of etiotropic drugs, as well as surgical methods of treatment.
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When prescribing etiotropic antibacterial drugs, it is necessary to take into account not only the sensitivity of the radiant fungus to them, but also the sensitivity of the accumulated bacterial flora. Due to the unsuccessful preliminary prescription of various groups of antibacterial drugs, the microflora associated with actinomycosis acquires antibiotic resistance, which becomes a serious problem in the selection of cialis tadalafil drugs.
Most often, in the treatment of the association of radiant fungus and bacteria, tetracycline drugs, benzylpenicillin, as well as drugs from the group of macrolides and fluoroquinolones are used.
Actinomycosis of the face is treated with the appointment of penicillins, coupled with clavulanic acid (Amoxiclav, Flemoclav) for a weekly course at a dose of 2.4 grams three times a day, then the dose is halved and the drug is continued for another seven days. Actinomycosis of the face only occasionally needs additional medication. A similar treatment regimen is suitable for the treatment of cervical actinomycosis.
In breast actinomycosis, the maximum dose of protected penicillins is not applied for seven days, but is extended to three to four weeks. Antibacterial drugs are administered parenterally. In severe cases, a combination of drugs from different groups can be used.
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If anaerobic bacteria are found in association with the radiant fungus, then antibiotics from the carbapenem group are used. they have the most balanced effect on anaerobic and aerobic microflora. Of the antifungal drugs used: Orungal, Diflucan, Nizoral, Lamisil and others.
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Immunotherapy has been used successfully in the treatment of actinomycosis. It allows you to increase the effectiveness of administered antibiotics and reduce their doses. For immunotherapy, Actinolysate is used. Actinolysate is a stabilized filtered culture liquid of self-lysing actinomycetes. A drug with proven high efficiency. In the treatment of actinomycosis, it is the most preferred of all immune preparations.
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The introduction of Actinolysate reduces the severity of the inflammatory reaction, significantly increases the efficiency of cellular immunity (phagocytosis), which is very important in advanced forms of actinomycosis, when the body is depleted.